Top 10 Microbiology News of 2020

2020 was the year of the horrific pandemic that influenced all aspects of our lives. Unfortunately, the scientific community was impacted too. Still, though the whole world scrambled to study the new virus, many scientific teams have made breakthroughs in other areas of microbiology and virology.

Bacteria were found to be more resourceful and resilient than previously thought. Some bacterial species were found to survive in under the ocean floor. Other bacteria apparently can produce their own carbon.

Top Microbiology News in 2020

Scientists manage to discover new species of giant viruses with unique properties in 2020. It seems bacteria can assist us in counteracting climate change and battle waste. Despite the losses the pandemic caused, the future of microbiology is bright and full of potential new discoveries.

1. Microbe that works double, and works hard: a new bacteria strain useful for wastewater treatment found [Singapore, October 2020]

1 Wastewater Treatment

Bacteria are crucial in detoxifying waste created by humans. These tiny organisms can break down toxic substances like ammonia and phosphates in wastewater. That is why wastewater plants usually put the waste through a reactor chain.

Each reactor in such a chain contains different types of bacteria. Due to their size, bacteria can perform a limited number of reactions and usually require specific conditions to grow. Therefore, each reactor has a limited number of bacterial species, and separate reactors are usually dedicated to specific processes. A team of Singapore researchers have sampled the bacterial communities in different reactors and has found the following:

  • There was a new strain of common wastewater bacteria, Thauera spp.
  • These bacteria can only live in anaerobic conditions.
  • In the anaerobic reactor containing this strain, the levels of nitrogen-containing compounds and phosphates were lower than usual.
  • The researchers have isolated the new strain called SND5.
  • It was found that SND5 could remove three types of substances – nitrites, nitrates, and phosphates at the same time.
  • SND5 used a novel mechanism for nitrogen removal not seen previously.
  • Later in 2021, another strain of the same genus Thauera was found.
  • This new strain was able to remove nitrogen even in unfavorable conditions with a low presence of carbon.
  • These discoveries would help make wastewater treatment more effective and cleaner in the future.

  • Reference: “Complete nitrogen removal via simultaneous nitrification and denitrification by a novel phosphate accumulating Thauera sp. strain SND5”. Accessed May 22, 2022. Link.

2. Elephant killing cyanobacteria – Researchers have found that microscopic microorganisms are behind the horrific death toll among elephants in Africa [Botswana, June 2020]

2 Elephant Killing Cyanobacteria

Sometimes some of the most significant organisms on Earth can be destroyed by something infinitely small. Since May 2020, more than 300 elephants have died in Botswana, a country in Southern Africa. It was established that those elephants were not killed by poachers. Researchers have taken samples from the fallen giants and have found the following:

  • Most of the dead elephants were found near sources of water.
  • The water sources were found to have an abnormal amount of cyanobacteria or blue-green algae.
  • These tiny microorganisms are known to produce dangerous neurotoxins.
  • When the number of algae in the water reaches a critical point, it can be dangerous to large organisms, elephants and humans alike.
  • Later analysis of the area revealed multiple cyanobacteria blooms in the area.
  • The scientists suggest that animals may die in large quantities in the future if the cyanobacteria spread again.

  • Reference: “Exceptional landscape-wide cyanobacteria bloom in Okavango Delta, Botswana in 2020 coincided with a mass elephant die-off event – ScienceDirect”. Accessed May 22, 2022. Link.
  • Reference: “350 elephants killed by ‘a combination of neurotoxins’ in water, Botswana government says | Live Science”. Accessed May 22, 2022. Link.

3. Using bacterial infection to combat malaria in mosquitoes – Researchers found that symbiotic bacteria in mosquitoes can suppress malaria pathogen [Kenya-UK, May 2020]

3 Malaria In Mosquitoes

Malaria is a dangerous infectious disease that is hard to destroy. Many countries in Africa and Asia still suffer from its impact. From repellents and nets to various medications, current measures are insufficient to eradicate malaria infection completely.

One of the reasons for this is that the malaria pathogen, Plasmodium falciparum, is transmitted through a mosquito’s bite. The spread and activity of mosquitoes are not easy to control. Multiple approaches targeting the malaria carrier have been proposed in the last decade.

Recently, a research project organized by scientists from the United Kingdom and Kenya has tested out an idea that is both safe and efficient:

  • The scientists’ primary mechanism consisted of using a microorganism that can act as a symbiont to the mosquito Anopheles arabiensis.
  • The search for the symbiotic organism in the mosquito resulted in using Microsporidia. This tiny microorganism is adapted to the mosquito midgut.
  • Microsporidia do not affect the ability of the mosquito to be active and procreate.
  • Microsporidia are transmitted from mother mosquitoes to offspring.
  • The presence of Microsporidia in the mosquito prevents the transmission of the malaria parasite, Plasmodium falciparum.
  • In fact, the presence of Microsporidia does not allow the Plasmodium to migrate and colonize the salivary glands of the mosquitoes, so they cannot transmit the parasite to another host.
  • One can potentially promote Microsporidia infection among populations of Anopheles spp. in malaria-affected areas to decrease the burden of the disease.

Later, in June 2021, a team of Indonesian scientists used a similar approach to prevent the spread of dengue virus. Their method used infection with Wolbachia, another well-known insect pathogen. Wolbachia infection causes the carrier mosquito, Aedes aegypti, to become sterile and drastically reduces their population, thus decreasing the likelihood of dengue virus spread. The approach was already applied in Singapore and led to the suppression of dengue virus in three years.


  • Reference: “A microsporidian impairs Plasmodium falciparum transmission in Anopheles arabiensis mosquitoes | Nature Communications”. Accessed May 22, 2022. Link.
  • Reference: “Efficacy of Wolbachia-Infected Mosquito Deployments for the Control of Dengue | NEJM”. Accessed May 22, 2022. Link.
  • Reference: “Towards a chlamydia vaccine | Nature Reviews Microbiology”. Accessed May 22, 2022. Link.

4. Bacteria as bogs for worms -Bacterial biofilms can deter earthworms, study finds [September 2020, China-Hong Kong]

4 Bacterial Biofilms

One of the most terrifying properties of bacteria is their ability to form biofilms. A bacterial biofilm is an association of multiple bacteria that work together and cover themselves with a matrix substance. This matrix protects them from various attacks. If a biofilm forms in a hospital setting – this matrix can become impenetrable for antibiotics. Not all bacteria that form biofilms live in humans or on medical devices. There are species of bacteria that live in the soil. These bacteria can often be food to soil-dwelling worms called nematodes.

A team of researchers from China, Hong Kong, and Singapore has decided to study the interactions of a well-known nematode, Caenorhabditis elegans, and a biofilm-forming bacteria, Pseudomonas aeruginosa:

  • The researchers have induced biofilm development in a colony of P. aeruginosa bacteria.
  • The researchers have also used mutant bacteria that have increased the production of exopolysaccharides compounds.
  • Then the worms were placed in a trap that contained the bacterial biofilms.
  • It was shown that the worms could not escape from biofilms that produced exopolysaccharides named Psl.
  • Another compound, alginate, also prevented the escape of predatory worms.
  • Such traps could protect the bacteria directly interacting with the nematode. They also provided a barrier protecting populations nearby.

C. elegans is not considered to be a harmful soil nematode. On the other hand, a group of soil nematodes can potentially damage plant roots. The main approach against such worms is using toxic compounds that can be very harmful to the soil ecosystem. Using bacterial traps instead can be potentially a cheap, effective, and safe method against there plant parasites.


  • Reference: “Biofilm matrix disrupts nematode motility and predatory behavior – PMC”. Accessed May 22, 2022. Link.

5. Bacteria can survive even in the depth of the sea – study finds that bacteria can survive under seafloor despite starvation [July 2020, Japan]

5 Ocean Floor

Bacteria can survive multiple extreme conditions. However, as a rule, these microorganisms need a steady source of carbon and oxygen or some other oxygen alternative in the case of anaerobic bacteria.

Such sources are rare in some regions of the world – for example, in-depth of the ocean. The lowest levels of the seafloor are often referred to as low productivity areas as there is almost no access to sunlight or potential nutrients. Nevertheless, colonies of bacteria can be found even there.

A team of Japanese researchers has decided to study the area called South Pacific Gyre. This area is sometimes called a “biological desert“. It is located very far from all continents. This area is said to have some of the most transparent water on the planet – and that is not a good thing for supporting life.

This part of the ocean is low on nutrients and chlorophyll, which means a low chance of photosynthesis. Considering how little food the upper layers of water contain, the ocean floor has even fewer feeding opportunities. There is also an added pressure of water above.

The scientists have taken probes from this ocean floor, composed of various sediments – a material made from multiple dead organisms and particles falling down on the ocean floor. The analysis of these sediments has shown that:

  • There were bacterial cells trapped in the sediments.
  • As the pores in the sediments were microscopic, the access to oxygen and other nutrients for the bacteria was very low.
  • The bacteria were probably trapped millions ago – as the sediment itself was dated to be around 100 million years old.
  • The quantity of the trapped bacteria was low – around 1000 microbial cells per probe.
  • There were two types of bacteria present: those that rely on oxygen (aerobic) and that live without oxygen (anaerobic).
  • When aerobic bacteria were put into a nutritive medium, they could grow and divide quickly. As a result, their colonies grew about 4 times in size.
  • Anaerobic bacteria had minimal growth in their own media.

These new data show that aerobic bacteria can grow in extremely poor conditions and under high pressure for a million years and still retain their ability to divide and grow if the conditions change.

This discovery has long-term implications, as global warming can cause the release of such bacteria from ice or ocean floor, and the properties of these microorganisms are unknown.


  • Reference: “Aerobic microbial life persists in oxic marine sediment as old as 101.5 million years | Nature Communications”. Accessed May 22, 2022. Link.

6. Pregnancy, microbes, and brain are linked – The composition of bacteria in a pregnant mother’s gut can determine the brain development of the baby, study finds [USA, September 2020]

6 Baby Brain Development

Humans serve as hosts to a variety of microbes. These microbes do not cause infections. Moreover – they are beneficial for multiple reasons. First, they form communities that live in various areas of the body. These communities are called microbiomes.

Recently, scientists have started to focus on one specific bacterial community that lives in our gut. Specialists try to find out what functions do bacteria play and what bacteria are better than others for our well-being.

A team of scientists from the University of California Los Angeles, USA, have posed a new question. We know that the microbiome in the gut changes throughout our lives and influences our well-being. Then what about the next generation?

To find out, the researchers used laboratory mice. First, they used two groups of mice: one group had all the microbes in the gut killed due to antibiotics or because the animals were initially raised germ-free.

The other group contained regular communities of bacteria. Both groups were female, and they gave birth to offspring. The researchers then investigated the state of the offspring and found out that:

  • The brain development in the mice born to mothers with little to no bacteria was altered.
  • The activity of genes in the brain of those young mice was different from a normal, healthy pattern.
  • This led to a delayed growth of nerve endings in the brain.
  • The nerve endings that were affected were mostly responsible for sensing the environment.
  • If the mothers were given a pre-made assembly of various bacteria, the brain deficiencies in their offspring did not develop.
  • It was found that the gut bacteria in mice produced several small molecules that influenced brain development in the developing babies.

This is the first study that shows that gut bacteria can influence brain development during pregnancy. It is yet unclear whether the same effect is present in humans, and this will require more research.

In 2021, many studies showed that diet can also influence the development of offspring byinfluencing the composition of bacteria in the gut.


  • Reference: “Maternal microbiota signals to the fetal brain | Nature Reviews Microbiology”. Accessed May 22, 2022. Link.

7. Coronavirus the hijacker – SARS-COV-2 virus can make infected cells move [USA-France, August 2020]

7 Sars Cov

The year 2020 was undoubtedly the year of SARC-COV-2, the infamous cause of coronavirus disease that has devastated the whole world. Scientists have painstakingly studied this new virus, deciphered its genome and observed its effects on various cells.

One such study undertaken by a joint team from USA and Pasteur Institute, Paris, France, has been devoted to studying the events after the virus infects cells.

  • The scientists added the virus into the culture of green monkey kidney cells.
  • The virus could successfully enter these cells.
  • After entering the cell, the virus changed multiple reactions within.
  • It led to a complete stop of normal cell development.
  • The cells also developed small “legs” on their surface called filopodia.
  • These filopodia contained single viruses themselves.
  • Cells with filopodia could make potential travel and interact with other cells. This way, they could spread the infection.
  • The scientists also established what major reactions the virus interfere with.

This study provided two major pieces of information. First, it has shown one of the mechanisms of spreading the virus within the body. The second important piece of data is that major cellular proteins are changed by the virus.

If the reactions led by the changed proteins could be blocked by drugs, the spread of coronavirus within the body could be stopped. Thus, a potential medical strategy could be developed.

In 2021, a team of Cuban researchers proposed a model drug that directly targets this filopodia-triggering mechanism.


  • Reference: “The Global Phosphorylation Landscape of SARS-CoV-2 Infection: Cell”. Accessed May 22, 2022. Link.

8. Bacterial kamikaze – bacteria have an altruistic strategy that ultimately kills few to protect many [USA, August 2020]

8 Antibiotic Resistance

We are all familiar with one of the major problems in the medical field – antibiotic resistance. Multiple mechanisms contribute to it. One of the major ones is the indiscriminate prescription of antibiotics and the incorrect dosages. So, the bacteria can adapt to the agents that kill them. But how they manage to adapt is still not understood properly.

A team of researchers at the University of Texas in Austin, USA, has focused on an interesting property of certain bacteria – swarming. Like bees, certain bacteria with propelling organs called flagella can form swarms.

While creating swarms, bacteria group tightly together, even forming complex figures. It was discovered that these bacterial swarms can survive antibiotics better than single bacteria. The researchers have decided to look into the mechanism of this resistance, as bacteria in swarms do not have any new antibiotic resistance genes:

  • The researchers chose widespread bacteria E.coli for their experiments.
  • The swarming colonies growing on media with antibiotics had different features than common antibiotic-resistant bacteria.
  • Bacteria that develop resistance to antibiotics usually slow down the activities in their cells.
  • On the other hand, swarming bacteria were active and divided at an average rate.
  • Also, swarming bacteria had two distinct groups within the colony.
  • One group was susceptible to antibiotics and died quickly.
  • These dead bacteria formed a protective circle around the survivors.
  • The surviving bacteria were more robust and withstood the adverse effects of the antibiotic agents.
  • It was found that the dead bacteria released a factor called AcrA.
  • The researchers named the factor a necrosignal.
  • Each bacterial species has its own necrosignal.
  • AcrA makes the surviving bacteria strengthen their walls and activate reactions that make them more resistant to stress.
  • Bacteria that do not swarm do not react to AcrA- like signals.

It is crucial to understand various resistance mechanisms in bacteria to improve the treatment of infections. Incidentally, in 2021, a similar mechanism exists in pathologic infectious fungi – yeasts. This mechanism provides resistance to antifungal agents.


  • Reference: “Dead cells release a ‘necrosignal’ that activates antibiotic survival pathways in bacterial swarms | Nature Communications”. Accessed May 22, 2022. Link.

9. Giant and dangerous virology treasure found in amoebas – scientists discovered a completely novel virus [Brazil-France, January 2020]

9 Amoeba

Amoebas have their own set of viruses. These amoebal viruses were discovered recently and are currently in the spotlight of virology research. They are often referred to as giant viruses because they are relatively more significant than those previously described.

Routine sampling in the artificial urban lake called Pampulha in Belo Horizonte, Brazil, has yielded a virus that was unlike any other:

  • The new virus was found in an amoeba called Acanthamoeba castellani.
  • The virus was large enough to show up in stained cells.
  • The virus has two capsid shells.
  • This new virus was named Yaravirus.
  • The sequencing of its genome has shown that the Yaravirus genes did not match any previously known viral genes in the database.
  • The virus was distantly related to another giant virus family, Mimiviridae.
  • Its genes also had some similarities to the genes of corals and bacteria.
  • This finding shows that viruses are even more diverse than previously thought.

Discoveries related to giant viruses were plentiful both in 2020 and later. Forinstance, genes of giant viruses were found in some algae.


  • Reference: “Yaravirus: A novel 80-nm virus infecting Acanthamoeba castellanii”. Accessed May 22, 2022. Link.

10. Hidden in the membrane – bacteria have proto-memories, study finds [Spain-USA – China, May 2020]

Bacterial biofilms have multiple properties that attract the attention of scientists. The formation of biofilms is partially dependent on electrical signals bacteria produce. These signals are generated with the help of protein structures called ion transport channels.

The channels transport ions with electrical charge across the bacterial membrane, thus creating a membrane potential. This can lead to an electrical signal.

A team of researchers from the University of San Diego, USA, have decided to study how these channels and the signals they generate change over time in response to light:

  • The team has chosen a bacteria species called Bacillus subtilis.
  • The researchers have exposed Bacillus subtilis biofilms to blue light.
  • It was found that blue light increases the negative charge of the bacterial membrane.
  • This process is dependent on the transport of the ions of potassium (K).
  • There is no reaction to light if the bacterial cells are deprived of a potassium channel through genetic engineering.
  • There was an exceptional reporter protein added to the bacteria that changes in response to the changes in the membrane charge.
  • Exposition to light leads to an immediate change in the reporter protein.
  • The changes in the bacterial membrane in response to light can remain in the biofilms for several hours.
  • This means that the bacteria can “remember” the influence of light.
  • This memory cannot be altered even if the conditions bacteria grow change.

The way bacteria react to the outside signal and retain their memory for a while resembles the process in neurons of higher animals. This is the first finding of such “proto memory” in bacteria.

In 2021, it was found that such memory is not limited to light signals. It was shown that bacteria can remember the exposure to toxins and develop resistance with each repeated addition of the toxic substance to the same population.


  • Reference: “Encoding Membrane-Potential-Based Memory within a Microbial Community: Cell Systems”. Accessed May 22, 2022. Link.

The pandemic has highlighted that we need to take infections – both bacterial and viral – seriously. And the active research in microbiology and virology in 2020 has also shown how complex the seemingly minuscule organisms are. For example, some bacteria in hot vents have chemical machinery that makes them able to destroy ethane.

Regular Bifidobacteria can work in unison with chemotherapy, destroy and invade cancer tumors. In addition, the composition of bacteria in our guts can determine if we can develop depression. In short, bacteria and viruses influence many aspects of life on Earth and our lives in particular. And it is essential to remember that small does not mean insignificant.

Cite This Page

APA7MLA8Chicago (2024, February 22). Top 10 Microbiology News of 2020. Bio Explorer. "Top 10 Microbiology News of 2020" Bio Explorer, 22 February 2024, "Top 10 Microbiology News of 2020" Bio Explorer, February 22 2024.
Key References
  • “350 elephants drop dead in Botswana, some walking in circles before doing face-plants | Live Science”. Accessed May 22, 2022. Link.
  • “CDC – DPDx – Malaria”. Accessed May 22, 2022. Link.
  • “Review of microsporidia-mosquito relationships: from the simple to the complex – PubMed”. Accessed May 22, 2022. Link.
  • “Wolbachia-mediated sterility suppresses Aedes aegypti populations in the urban tropics | medRxiv”. Accessed May 22, 2022. Link.
  • “Bacterial Biofilm and its Role in the Pathogenesis of Disease – PMC”. Accessed May 22, 2022. Link.
  • “The Use of Plant Growth-Promoting Bacteria to Prevent Nematode Damage to Plants – PMC”. Accessed May 22, 2022. Link.
  • “South Pacific Gyre – microbewiki”. Accessed May 22, 2022. Link.
  • “Maternal high sugar and fat diet benefits offspring brain function via targeting on the gut-brain axis – PubMed”. Accessed May 22, 2022. Link.
  • “Targeting CK2 mediated signaling to impair/tackle SARS-CoV-2 infection: a computational biology approach | Molecular Medicine | Full Text”. Accessed May 22, 2022. Link.
  • “A statistical physics view of swarming bacteria | Movement Ecology | Full Text”. Accessed May 22, 2022. Link.
  • “The adaptive role of cell death in yeast communities stressed with macrolide antifungals | bioRxiv”. Accessed May 22, 2022. Link.
  • “Giant Viruses | American Scientist”. Accessed May 22, 2022. Link.
  • “Giant virus genomes discovered lurking in DNA of common algae | Science | AAAS”. Accessed May 22, 2022. Link.
  • “Species-Independent Attraction to Biofilms through Electrical Signaling – PubMed”. Accessed May 22, 2022. Link.
  • “Bacterial Ion Channels – PubMed”. Accessed May 22, 2022. Link.
  • “Microorganisms | Free Full-Text | Cellular Memory of HipA-Induced Growth Arrest: The Length of Cell Growth Arrest Becomes Shorter for Each Successive Induction | HTML”. Accessed May 22, 2022. Link.
  • “New ethane-munching microbes discovered at hot vents”. Accessed May 22, 2022. Link.
  • “Researchers Surprised That Gut Bacteria Penetrates Tumors – Improves Cancer Therapy”. Accessed May 22, 2022. Link.
  • “Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system | Nature Communications”. Accessed May 22, 2022. Link.


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