Top : Methods and Protocols : Biophysics
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Crystallization of protein-nucleic acid complexes
- A prerequisite for the determination of the three-dimensional structure of a protein-nucleic acid complex by x-ray crystallography is a well-ordered crystal of the complex in question. This article describes methods for crystallizing these complexes, including protein sample, choice of oligonucleotide, preparation of complexes, and crystallization conditions.
http://muddy.med.jhmi.edu/wolberger/protein-DNA.html
Added: 25-Jun-2000 Hits: 902 Rating: 1.00 Votes: 1
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